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After ingestion, the psilocybin is enzymatically converted to psilocin. Absorbed from the gastro-intestinal tract, hallucinogenic effects usually occur within 30 minutes of ingestion with a duration of effect of 4—6 hours.
Various terms have also been used by users for various forms of psilocybin and psilocin or mushrooms containing these hallucinogens: The potency depends on species, origin, growing conditions and harvest period. The most potent species, e.
The maximum amount of psilocybin and psilocin in Psilocybe cubensis ordinary psilocybe is about 0. The average percentage of active ingredients in dried mushrooms is about 10 times as high as in fresh mushrooms. Variations in potency are lower in cultivated mushrooms than in those growing in the wild. Some hallucinogenic mushrooms contain various amounts of phenethylamine. Phenylethylamine is a sympathomimetic amine ; it can be responsible for cardiovascular effects tachycardia and other unwanted reactions.
Reports from the United States suggest that often mushrooms sold as hallucinogenic mushrooms prove to be normal grocery-bought mushrooms laced with LSD, PCP phencyclidine or other substances. In an year study, samples that were said to be psilocybin were analysed. Only 28 percent of these were hallucinogenic mushrooms, while 35 percent were other drugs, mostly LSD or PCP, and 37 percent contained no drug at all. However, the control of the mushrooms that contain these substances is interpreted in many different ways across Europe.
Probably this reflects the extent to which they grow freely in certain conditions, and the fact that they appear to be a somewhat regional phenomenon. For example, in some European countries, the law specifically lists hallucinogenic mushrooms themselves as a controlled substance and forbids their sale or possession. Other countries simply treat the mushrooms as being the controlled substances of psilocin or psilocybin in compound form.
Some look at the intent of the act; they ban cultivation, possession or sale only when for the purposes of abuse. Their condition is also considered — fresh mushrooms might not be considered illegal, but prepared or treated mushrooms are illegal — again perhaps reflecting the intent. Finally, a number of countries remain with unclear legislation, simply as there have been so few cases that have come to court. Due to low prevalence questions about the use of hallucinogenic mushrooms are not routinely included in general population surveys.
The prices of the kits vary between EUR 23—, depending on the type of hallucinogenic mushroom species for which spores are available. At present, there are no medical indications for psilocin or psilocybin. Recent research with psilocybin has been reported on the treatment of compulsive disorders in humans.
In the past few years, a growing number of studies using human volunteers have begun to explore the possible therapeutic benefits of drugs such as psilocybin, LSD, DMT, MDMA, ibogaine and ketamine.
These studies are looking at psilocybin and other hallucinogens to treat a number of otherwise intractable psychiatric disorders, including chronic depression, post-traumatic stress disorder, and drug or alcohol dependency. Brown, D.
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